Affiliation:
1. Obstetrics & Gynecology Hospital of Fudan University
Abstract
Abstract
Objective: To investigate vascular characteristics and prognosis of gestational trophoblastic neoplasia (GTN) with uterine arteriovenous malformation(UAVM) Methods: Forty-four patients with GTN at our hospital from December 2015 to December 2020 were selected. Imaging characteristics of MRI and CE-MRA before treatment, treatment methods, and the prognosis were followed-up. Results: A total of 44 cases were included, including five cases of placental site trophoblastic tumor (PSTT) and 39 cases of the other GTN. There were two cases of PSTT combined with UAVM and 23 cases of the other GTN combined with UAVM. Thirty-nine cases of the other GTN were divided into two groups according to the presence or absence of UAVM. Data regarding the β-human chorionic gonadotropin value (<10,000 mIU/mL and ≥10,000 mIU/mL) were evaluated using Chi-square test (P = 0.001); the difference was statistically significant (P < 0.05). The average FIGO scores of the two groups were 4.19 (±3.69) and 6. 70 (±3.39) (P = 0.035); the difference was statistically significant (P < 0.05). Vascular characteristics of all the patients were analyzed.Conclusion: Most of the lesions are supplied by uterine arteries and drained by uterine veins and ovarian veins. When β-hCG is ≥10,000 mIU/mL, the probability of UAVM increased. The higher the prognosis score, the greater the possibility of UAVM.
Publisher
Research Square Platform LLC