Catheter-based renal sympathetic denervation may not be appropriate for the treatment of hypertension caused by primary aldosteronism: a case report

Author:

Wang Li1,Li Zhuqing1,Li Chao1,Lu Chengzhi1

Affiliation:

1. The First Affiliated Central Hospital of Nankai University

Abstract

Abstract Previous studies on the treatment of hypertension with RDN were all aimed at patients with essential hypertension, while there were few studies on secondary hypertension, especially primary aldosteronism. Whether RDN can be used to treat hypertension due to primary aldosteronism remains a subject of much debate. Here, we present a 54-year-old man with a history of resistant hypertension spanning more than 10 years; secondary hypertension was ruled out 6 years ago, and he underwent renal sympathetic denervation(RDN) in 2016. The patient's blood pressure had been controllable after half a year of RDN. After six months, the patient's blood pressure began to rise gradually and he began to increase the type of antihypertensive medication. The patient was diagnosed with aldosteronoma 1 year ago and underwent laparoscopic adrenalectomy. After that, the patient's blood pressure controlled well.

Publisher

Research Square Platform LLC

Reference5 articles.

1. Thirty-six-month results of laparoscopic-based renal denervation plus unilateral laparoscopic adrenalectomy for the treatment of patients with resistant hypertension caused by unilateral aldosterone-producing adenoma;Liu Y;J Clin Hypertens (Greenwich),2021

2. Wang Li, Lu CZ, Zhang X et al. Effect of catheter based radiofrequency ablation on refractory hypertension patients with high renin levels.Zhong hua gao xue ya za zhi. 2014. 22(11): 1084–6. (Article in Chinese).

3. Changes in Plasma Renin Activity After Renal Artery Sympathetic Denervation;Mahfoud F;J Am Coll Cardiol,2021

4. Yang X, Lin L, Zhang Z, Chen X. Effects of catheter-based renal denervation on renin-aldosterone system, catecholamines, and electrolytes: A systematic review and meta-analysis. J Clin Hypertens (Greenwich). 2022.

5. Letter to editor on "Thirty-six-month results of laparoscopic-based renal denervation plus unilateral laparoscopic adrenalectomy for the treatment of patients with resistant hypertension caused by unilateral aldosterone-producing Adenoma;Schiavone D;J Clin Hypertens (Greenwich),2022

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