Cystic squamous metaplasia in a giant benign phyllodes tumor of the breast: A case report

Author:

Niyonkuru Evrard1ORCID,Nisabwe Simon1,Sami Zineb2,Faizi Issam2,Mazti Asmae1,Elkarroumi Mohamed2,Karkouri Mehdi1

Affiliation:

1. Department of Pathology, Ibn Rochd University Hospital Center, Casablanca, Morocco

2. Mohammed VI Center for Cancer Treatment, Ibn Rochd University Hospital Center, Casablanca, Morocco

Abstract

Abstract Background Phyllodes tumor is rare tumor of the breast, which encompasses both stromal and epithelial components. In these components, metaplastic changes can be observed occasionally. Case presentation We report the case of a 51-year-old woman nulligest menopaused who presented a huge mass, largely ulcerated in her right breast. The radiological examination revealed a large tumor with microcalicifications classified as Breast Imaging and Reporting Data System [BI-RADS] category 5. The patient undergone right mastectomy and the histological analysis revealed benign phyllodes tumor with cystic squamous metaplasia. Conclusions It is essential to be aware of this uncommon event in order to avoid misdiagnosis.

Publisher

Research Square Platform LLC

Reference14 articles.

1. WHO, Classification of Tumours Editorial Board. Breast tumours, (WHO classification of tumours series. Volume 2, 5th ed. IARC, Lyon (France); 2019.

2. Schnitt SJ, Collins LC. Bıopsy Interpretation Series Biopsy Interpretation of the Breast: Phyllodes Tumor 2th ed. Philadelphia 2013; 186–199.

3. A huge benign phyllodes tumour of the breast: a rare entity;Paryani;Indian J Surg Oncol,2019

4. Giant benign mammary phyllodes tumor: report of a case and review of the literature;Fernández-Ferreira R;Case Rep Oncol,2021

5. Phyllodes tumors of the breast: The role of pathologic parameters;Tan PH;Am J Clin Pathol,2005

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