A Chinese Scoring System for Predicting Successful Retrograde Collateral Traverse in Patients with Total Chronic Coronary Occlusion

Author:

Li Qiuyu1ORCID,Lin Xiao Long2,Li Fan Qi3,Cheng Zi Chao4,Tian Jia Yu1,Zhao Dong Hui5,Lau Wayne Bond6,Liu Jing Hua4,Fan Qian1

Affiliation:

1. Center for Coronary Artery Disease, Beijing Anzhen Hospital, Capital Medical University, and Beijing Institute of Heart, Lung, and Blood Vessel Disease, Beijing, 100029, China

2. Center for Coronary Artery Disease, Beijing Anzhen Hospital, Capital Medical University, and Beijing Institute of Heart, Lung and Blood vessel Disease, Beijing 100029, China

3. Center for Coronary Artery Disease, Bejing AnZhen Hospital, Capital Medical University, and Beijing Institute of Heart, Lung, and Blood Vessel Disease, Beijing, 100029, China

4. Center for Coronary Artery Disease, Beijing AnZhen Hospital, Capital Medical University, and Beijing Institute of Heart, Lung, and Blood vessel Diseases, Beijing, 100029, China

5. Center for Coronary Artery Disease, Beijing AnZhen Hospital, Capital Medical University, and Beijing Institute of Heart, Lung and Blood Vessel Disease, Beijing, 100029, China

6. Thomas Jefferson University

Abstract

Abstract Background Retrograde approach technique has been challenging in percutaneous coronary interventional treatment of chronic total occlusion (CTO) coronary disease. The present study endeavors to determine a novel Chinese scoring system for predicting successful collateral channels traverse via retrograde approach. Methods The demographic characteristics and angiographic characteristics of 309 CTO patient were analyzed by univariate and multivariate analysisfor selecting potential predictors. And the nomogram was used to establish the scoring system. Then it was evaluated by the internal and external validation. Results The predictors of Age, Connections between collateral channels and recipient vessels, and Channel Tortuosity (ACT) were identified with multivariate analysis and employed to the ACT score system. With acceptable calibrations, the AUC of the scoring system and the external validation were 0.826 and 0.816 respectively. Based on score, the predictors were divided into three risk categories and it showed a consistent prediction power in the validation cohort. Conclusions The novel Chinese ACT score is a reliable tool for predicting successful retrograde collateral traverse.

Publisher

Research Square Platform LLC

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