Abstract
Background
Hepatic malignant tumors present a significant global health challenge, often treated with percutaneous microwave ablation (MWA). Understanding the efficacy of MWA and factors influencing tumor recurrence is crucial for improving patient outcomes.
Methods
This study analyzed 101 out of 249 patients with hepatic malignant tumors treated at the Shandong Cancer Hospital and Institute. Disease-free and overall survival rates at 1, 2, and 3 years post-MWA were assessed, and correlations between tumor recurrence and variables such as Child-Pugh B liver function classification and lesion count were investigated. Additionally, a meta-analysis was conducted to determine independent risk factors for recurrence post-MWA treatment.
Results
The study revealed disease-free survival rates of 80.2%, 72.3%, and 70.3% at 1, 2, and 3 years post-MWA, with overall survival rates of 99%, 97%, and 96%. Significantly, notable associations were identified between tumor recurrence and Child-Pugh B classification, as well as the number of lesions. The meta-analysis further confirmed lesion count and Child-Pugh B classification as independent risk factors for recurrence following MWA.
Conclusion
Factors such as Child-Pugh B classification and lesion count play a critical role in predicting tumor recurrence post-MWA treatment in hepatic malignant tumors. These findings provide valuable insights for clinicians in decision-making and post-treatment monitoring strategies, ultimately contributing to enhanced patient care and outcomes.