Magnetic Nanoparticle Supported Choline Chloride-Glucose (Deep Eutectic Solvent) for the One-Pot Synthesis of 3,4-Disubstituted Isoxazole-5(4H)-ones

Author:

Atharifar Hengameh1,Keivanloo Ali1,Maleki Behrooz2,Baghayeri Mehdi3,Alinezhad Heshmatollah2

Affiliation:

1. Shahrood University of Technology

2. University of Mazandaran

3. Hakim Sabzevari University

Abstract

Abstract One efficient method for the synthesis of 3,4-disubstituted isoxazole-5(4H)-ones derivatives catalyzed magnetic deep eutectic solvent is reported. The structure of the nano-catalyst was characterized by FE-SEM, FT-IR, EDX, and TGA. Then, the excellent activity of the catalyst was displayed for the synthesis of 3,4-disubstituted isoxazole-5(4H)-ones derivatives. This heterogeneous catalyst can be easily recovered via a magnetic field and reused for subsequent reactions. Easy workup, high yields in a short time and non-toxic catalyst are the main merits of this method.

Publisher

Research Square Platform LLC

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