Affiliation:
1. Department of Psychiatry, Wuhan Mental Health Center, Wuhan, China
Abstract
Abstract
Metabolic syndrome (MetS) is a common comorbidity of major depressive disorder (MDD) that has serious adverse effects on physical health. The purpose of this study is to investigate the prevalence and factors influencing MetS in patients hospitalized for their first episode of MDD. The study included 981 patients who were admitted for MDD. Data on demographic and clinical characteristics were gathered, along with measurements of metabolism-related parameters and assessments of psychological and psychopathological symptoms. The prevalence of MetS in the study population was 9.68%. Patients with both MDD and MetS were found to have more extensive and significant demographic and clinical characteristics, higher levels of metabolism-related parameters, and more severe psychological and psychopathological symptoms. Risk factors for the diagnosis of MetS included the onset age of MDD, higher HAMD scores, and higher TSH levels. The risk factors for higher MetS scores included older age, being married, higher PSS scores, and higher levels of TSH and TC, while higher levels of LDL-C were protective. Our results suggest that MetS is not highly prevalent in patients with MDD, but certain risk factors may increase its likelihood and severity.
Publisher
Research Square Platform LLC