Abstract
Granulomatous hypophysitis (GRH) is an extremely rare inflammatory disease of the pituitary. GRH commonly presents with nonspecific clinical and radiological patterns and is commonly misdiagnosed as pituitary adenoma—a 48-year-old male patient presented with a one-week history of headache, dizziness, and blurred vision. An MRI scan confirmed the diagnosis of pituitary adenoma, and further evaluation revealed decreased levels of thyrotropin, indicating pituitary dysfunction. The patient underwent transnasal sella resection, during which inflammatory hyperplastic tissue was identified. Post-surgery, the patient received glucocorticoid shock therapy, resulting in significant relief of symptoms. In this study, we retrospectively analyzed the clinical data of a patient diagnosed with granulomatous pituitaritis through operation and pathology. We discussed the patient's clinical manifestations, imaging characteristics, and treatment methods by incorporating relevant literature from both domestic and international sources.