Clinical profile and treatment of patients with Vulvar Cancer: experience from a novice Gynecologic Oncology unit in Sub Saharan Africa

Author:

Birara Malede1,Gudu Wondimu1,Mekonen Tadios1,Abdu Amani1

Affiliation:

1. St. Paul’s Hospital Millennium Medical College

Abstract

Abstract

Introduction Vulvar cancer is rare accounting approximately for 4% of gynecologic malignancies. The prevalence of vulvar cancer rising in sub-Saharan Africa primarily attributed to high incidence of HIV infections. This study aims to explore clinic-pathologic profile and treatment of patients at a novice gynecologic oncology unit in Ethiopia. Methodology A descriptive cross-sectional study was conducted, among vulvar cancer patients treated at Saint Paul’s Hospital millennium medical college in Ethiopia, gynecology oncologic unit from 2016 to 2020. Data was collected from patients’ medical records and hospital registries using a simple data extraction format. Data was analyzed using IBM SPSS 23.1 computer statistical software. Results The magnitude of vulvar cancer was 3.6%, with mean age of patients being 42 years. Commonest symptoms were vulvar swelling, itching, and ulceration. The average duration of symptoms was 12 months and 66 percent of patients were HIV positive. The mean lesion size was 5 cm, with squamous cell carcinoma being the most prevalent (82%). Disease was early stage in 56% percent of patients. Fifty seven Percent were given treatment. Surgery was done to 37% of patients, postoperative wound complications rate being 30 percent. 43 percent had Postoperative follow-up and among those who adhered to follow-up, 85 individuals were disease-free at the last assessment, with only one case of recurrent disease. Conclusions Vulvar cancer is not uncommon being more prevalent among HIV patients. Early diagnosis and staging are crucial for improved patient outcomes. Interventions to raise awareness, implementing screening programs, and ensuring early referrals are imperative.

Publisher

Research Square Platform LLC

Reference10 articles.

1. Changes in the Clinico pathological Demographics of Vulvar Cancer in Japan: Increasing Oldest-Old, Stage Shifting, and Decreasing Cohort-Level Survival;Nishio S;J Clin Med,2019

2. Oguntayo O, Adekunle ZSM, Adewuyi A, Sunday, Kolawole O, Abimbola TR, Ismail Habiba, Koledade A, Korede. The pattern of carcinoma of the vulva in Zaria, Northern Nigeria. Nigerian Journal of Basic and Clinical Sciences; 2016.

3. Vulvar cancer: epidemiology, clinical presentation, and management options;Alkatout I;Int J women's health,2015

4. Cancer of the vulva;Rogers LJ;Int J Gynecol Obstet,2018

5. Vulvar cancer in Ethiopia: A cohort study on the characteristics and survival of 86 patients;Kroeber ES;Medicine,2018

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3