Relationship between weight-adjusted waist circumference index and psoriasis - based on data from NHANES2009-2014

Abstract

Abstract Objective This study aims to investigate the potential relationships between a novel obesity indicator,the weight-adjusted-waist index (WWI),and psoriasis.Methods A cross-sectional design was used in this study,featuring both psoriasis and non-psoriasis subjects with complete WWI data,sourced from the National Health and Nutrition Examination Survey (NHANES) spanning 2009 to 2014.To determine the relationship between the WWI and psoriasis,both univariate and multivariate logistic regression models,which were appropriately weighted,were used in the analysis.The linearity of the relationships was validated using smooth curve fitting. Additionally,subgroup evaluations and interaction assessments were conducted.Results The study sample comprised 15031 subjects, yielding a psoriasis prevalence of 2.76%.WWI was positively related to psoriasis according to the full adjustment [odds ratio (OR) = 1.53,95% confidence interval (95%CI) = 1.02,2.26,P = 0.036].After converting the WWI to a categorical variable by quartiles (Q1-Q4),compared to Q1 the highest WWI quartile was linked to an obviously increased likelihood of psoriasis(OR = 2.62,95%CI = 1.17,5.590, P = 0.0109).Conclusion This study provides evidence that an elevated WWI is correlated with an increased risk of psoriasis in the adult population of the U.S. These results suggest that the WWI may serve as a viable anthropometric indicator for predicting psoriasis.