Affiliation:
1. Henan University of Chinese Medicin
2. People’s Hospital of Henan University of Chinese Medicine, People’s Hospital of Zhengzhou
3. Luohe Central Hospital
4. Henan Research Centre of Cardiopulmonary-Cerebral Resuscitation Engineering Technology
Abstract
Abstract
Background
After cardiopulmonary resuscitation (CPR), paroxysmal sympathetic hyperactivity (PSH) will appear due to extensive brain injury. PSH is a serious clinical syndrome, and it is often treated with drugs. However, the application of hyperbaric oxygen in the treatment(HBOT) of PSH is rarely reported in the literature.We aimed to investigate the clinical effects of single-chamber pure oxygen treatment on PSH following CPR.
Methods
We retrospectively analysed clinical data of four patients treated at our hospital who developed signs of PSH post-CPR and received HBOT at an early stage to assess the clinical effects of HBOT on PSH.
Results
Following 3–4 HBOT sessions, signs of PSH were substantially diminished, and patients’ Clinical Symptom Scale scores decreased significantly. The time to awakening was 34, 25, 38, and 28 days for cases 1–4, respectively.
Conclusions
HBOT alleviated PSH, reduced brain damage, and promoted a return to full consciousness. HBOT efficacy was significant in these patients, and promoting HBOT in the clinical setting is recommended.
Publisher
Research Square Platform LLC