A comparative study of midstream urine culture and stone culture in patients undergoing ureteroscopic stone removal

Abstract

Abstract Background The purpose of this study was to see the correlation between urine and stone cultures in individuals who had ureteroscopic stone removal. Methods This is a prospective comparative observational study of patients who had ureteroscopic stone removal from September 2019 to March 2021. A total of 50 patients were included in our study. Midstream urine sample was collected 7 days before surgery and sent for culture, stone collected during surgery were also sent for culture. The association between preoperative urine culture and intraoperative stone culture, as well as the bacterial flora in both cultures, was investigated. Results 64% of patients were males, and 36% were females.16% of patients had positive urine culture compared to 42% positive stone culture.12% of patients were positive for both stone and urine culture. Only 4% of the time, the bacteriological investigation revealed the same pathogen. E. coli was the most common pathogen in urine culture, while enterobacter was the commonest organism in stone culture. The sensitivity, specificity, PPV, NPV, and diagnostic accuracy of urine culture versus stone culture were calculated to be 28.57 percent, 93.10 percent, 75 percent, 64.28 percent, and 66 percent, respectively. Conclusions Pre-operative urine cultures have a low predictive value and diagnostic accuracy for infective organisms in ureteric stones. As a result, stone culture should be incorporated into standard procedures for stone removal during endourological surgery.