Clinical, Endoscopic, Pathological Characteristics and Managements of Cap Polyposis: A Real-world Study from China

Abstract

Abstract Background and aims: Cap polyposis (CP) is a rare kind of benign disease, and the majority of previously published articles on it involve a small number of patients. Hence, we summarized our experience to add more data, hoping to raise awareness of this disease. Methods From January, 1st, 2017 to November, 1st, 2021, consecutive patients diagnosed with CP were retrospectively reviewed. Their medical histories, and laboratory, imaging, endoscopic, and pathology results were analyzed. We made telephone calls to the patients and searched for the information in our electronic medical records to obtain the follow-up results. Results Forty-one patients were chosen for analysis. The median age of the patients was 20 years old, and 90.24% (37 patients) of the patients were male. There were multiple and combined treatments for these patients. These treatments can be mainly divided into 3 categories: medical therapy, endotherapy and surgery. Medical therapy could help to diminish the size of the polyps but was difficult to resolve; however, the patients’ symptoms could be diminished. Twenty-three patients received surgical resection, and 12 patients received endotherapy. We further compared the two methods of polyp resection. Both endotherapy and surgery were safe, and the recurrence risk was not significantly different between the two kinds of therapy (P = 0.321). Conclusions The clinical improvement of medical treatments was not satisfactory, and endotherapy or surgical resection could remove the polyposis and provide temporary relief, but the recurrence rates were high.