MtDNA variation within local human populations in Bosnia and Herzegovina

Author:

Kapur-Pojskic Lejla1,Pojskic Naris1,Radosavljevic Gabrijela1,Marjanovic Damir1,Hadziselimovic Rifat1

Affiliation:

1. University of Sarajevo, Institute for Genetic Engineering and Biotechnology, Sarajevo, Bosna i Hercegovina

Abstract

Being a crossroad of many ancient and recent historical migrations, Bosnia and Herzegovina (B&H) represents unique spot of multicultural and social diversity. The main aim of this study was to assess genetic structure of three local populations of mountain area from central part of B&H using mtDNA HVS-1 as an informative marker for population genetics studies. A 444 bp HVS-1 segment of control region of mtDNA extracted from buccal swabs was PCR amplified and sequenced. Haplotype and nucleotide diversity, average number of nucleotide differences, AMOVA and pairwise FST based on mtDNA haplotype and haplogroup frequencies were calculated. NJ tree was constructed based on pairwise FST results. Tajima?s D was calculated to evaluate population demographic status.

Publisher

National Library of Serbia

Subject

Plant Science,Genetics

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