Affiliation:
1. University of Sarajevo, Institute for Genetic Engineering and Biotechnology, Sarajevo, Bosna i Hercegovina
Abstract
Being a crossroad of many ancient and recent historical migrations, Bosnia
and Herzegovina (B&H) represents unique spot of multicultural and social
diversity. The main aim of this study was to assess genetic structure of
three local populations of mountain area from central part of B&H using mtDNA
HVS-1 as an informative marker for population genetics studies. A 444 bp
HVS-1 segment of control region of mtDNA extracted from buccal swabs was PCR
amplified and sequenced. Haplotype and nucleotide diversity, average number
of nucleotide differences, AMOVA and pairwise FST based on mtDNA haplotype
and haplogroup frequencies were calculated. NJ tree was constructed based on
pairwise FST results. Tajima?s D was calculated to evaluate population
demographic status.
Publisher
National Library of Serbia