Affiliation:
1. Clinical Center of Serbia, Institute of Obstetrics and Gynecology, Belgrade
2. Clinical Center of Serbia, Institute of Obstetrics and Gynecology, Belgrade + Faculty of Medicine, Belgrade
3. Center for Anesthesiology and Resuscitation, Belgrade + Faculty of Medicine, Belgrade
Abstract
Background/Aim. Concerning the growth of ovarian carcinoma incidence and bad
prognosis for malignant forms, early and precise diagnostics is gaining in
importance as a condition for precise and appropriate therapy for ovarian
tumor masses. The aim of this study was to analyze pre- and postoperative
findings of patients with adnexal masses in order to identify factors which
could predict the nature and stage of the tumor prior to surgery. Methods.
All patients with adnexal masses who were treated in a 6-month period in the
Institute of Obstetrics and Gynecology, Clinical Center of Serbia, (IOG,
CCS), Belgrade, had their epidemiologic and gynecologic anamnesis and
standard laboratory analyses taken prior to surgery. Also, clinical and
ultrasonographic check up of pelvic organs was performed, as well as
calculation of body mass index (BMI) and risk of malignancy index (RMI).
After surgery we analyzed histopathological (HP) findings of tumors as a mean
of final diagnosis and staging. For statistical analysis, we used SPSS 15
program. Results. Throughout a 6-month period, we examined 81 patients with
adnexal masses treated in the IOG CCS. HP findings showed that there were
significantly more benign (n = 51) than malignant (n = 30) tumors in all the
patients (?2 = 5.512). The patients with malignant HP findings were
significantly older than those with benign adnexal masses (t = 3.362; p =
0.001). Significantly more patients with malignant HP findings were in
menopause (p = 0.034). BMI values were highly significantly higher in the
patients with malignant adnexal tumors (t = 3.421; p = 0.001). There was a
statistically significant positive correlation between HP categories (benign,
malignant) and RMI categories (low, intermediate and high risk) of all the
patients (high risk, more malignant HP) (Roxy = 0.428; df = 78; p = 0.000).
Conclusion. Patients in menopause, especially older ones, with high BMI and
RMI should immediately be referred to a tertiary level institution, where
appropriate surgery could be performed.
Publisher
National Library of Serbia
Subject
Pharmacology (medical),General Medicine
Cited by
11 articles.
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