Affiliation:
1. Faculty of Medicine, Novi Sad + Clinical Center of Vojvodina, Gynecology and Obstetrics Clinic, Novi Sad, Serbia
2. Outpatient Clinic „Sveti Vračevi“, Bijeljina, Bosnia and Herzegovina
3. Faculty of Medicine, University of Novi Sad, Novi Sad + §Institute for Children and Youth Health Care of Vojvodina, Novi Sad
Abstract
Background/Aim. According to the World Health Organization (WHO) definition,
congenital anomalies are all disorders of the organs or tissues, regardless
of whether they are visible at birth or manifest in life, and are registered
in the International Classification of Diseases. The aim of this study was to
compare the incidence and structure of prenatally detected and clinically
manifested congenital anomalies in the newborns in the region of Novi Sad
(Province of Vojvodina, Serbia) in the two distant years (1996 and 2006).
Methods. This retrospective cohort study included all the children born at
the Clinic for Gynecology and Obstetrics (Clinical Center of Vojvodina) in
Novi Sad during 1996 and 2006. The incidence and the structure of congenital
anomalies were analyzed. Results. During 1996 there were 6,099 births and
major congenital anomalies were found in 215 infants, representing 3.5%. In
2006 there were 6,628 births and major congenital anomalies were noted in 201
newborns, which is 3%. During 1996 there were more children with anomalies of
musculoskeletal system, urogenital tract, with anomalies of the central
nervous system and chromosomal abnormalities. During the year 2006 there were
more children with cardiovascular anomalies, followed by urogenital
anomalies, with significant decline in musculoskeletal anomalies. The
distribution of the newborns with major congenital anomalies, regarding
perinatal outcome, showed the difference between the studied years. In 2006
the increasing number of children required further investigation and
treatment. Conclusions. There is no national registry of congenital anomalies
in Serbia so the aim of this study was to enlight this topic. In the span of
ten years, covering the period of the NATO campaign in Novi Sad and Serbia,
the frequency of major congenital anomalies in the newborns was not
increased. The most frequent anomalies observed during both years implied the
musculosketelal, cardiovascular, urogenital and central nervous system. In
the year 2006 there was a significant eruption of cardiovascular anomalies
and a significant decrease of musculoskeletal anomalies, chromosomal
abnormalities and central nervous system anomalies, while the number of
urogenital anomalies declined compared to the year 1996.
Publisher
National Library of Serbia
Subject
Pharmacology (medical),General Medicine
Cited by
1 articles.
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