Affiliation:
1. Department of Organic Chemistry, University of Plovdiv, Plovdiv, Bulgaria
Abstract
Herein we report an alternative eco-friendly method for the synthesis of 1,2,3,4-tetrahydroisoquinoline sulfonamide derivatives. All obtained compounds were screened for their in vitro inhibition of albumin denaturation, antioxidant, antitryptic and antibacterial activity, and have shown significant results. The lipophilicity was established using both reversed-phase thin layer chromatography and in silico calculations.
Publisher
National Library of Serbia