GC-MS profiling of bioactive extracts from Haberlea rhodopensis: An endemic resurrection plant-Reference-Cited by-同舟云学术

GC-MS profiling of bioactive extracts from Haberlea rhodopensis: An endemic resurrection plant

Published:2011 Issue:2 Volume:76 Page:211-220
ISSN:0352-5139
Container-title:Journal of the Serbian Chemical Society
language:en
Short-container-title:JSCS

Author:

Berkov Strahil¹,Nikolova Milena²,Hristozova Nevena³,Momekov Georgi⁴,Ionkova Iliana⁴,Djilianov Dimitar¹

Affiliation:

1. AgroBioInstitute, Sofia, Bulgaria

2. Institute of Botany, Bulgarian Academy of Sciences, Sofia, Bulgaria

3. Faculty of Biology, Sofia University, Sofia, Bulgaria

4. Faculty of Pharmacy, Medical University of Sofia, Sofia, Bulgaria

Abstract

GC-MS metabolic profiling of the apolar and polar fractions from methanolic extracts of Haberlea rhodopensis revealed more than one hundred compounds (amino acids, fatty acids, phenolic acids, sterols, glycerides, saccharides, etc.). Bioactivity assays showed that the polar fractions possessed strong free radical scavenging activity (IC50 - 19.95 ?14.11 ?g ml-1 for fresh leaves and 50.04 ?23.16 ?g ml-1 for desiccated leaves), while both the polar and apolar fractions failed to provoke any significant cytotoxic effects against the tested cell lines. Five compounds possessing antiradical activity were identified - syringic, vanillic, caffeic, dihydrocaffeic and p-coumaric acids.

Publisher

National Library of Serbia

Subject

General Chemistry

Reference11 articles.

1. Responses of the resurrection plant Haberlea rhodopensis to high irradiance

2. Desiccation increases sucrose levels in Ramonda and Haberlea, two genera of resurrection plants in the Gesneriaceae

3. Role of phenolics in the antioxidative status of the resurrection plant Ramonda serbica during dehydration and rehydration

4. The predominant polyphenol in the leaves of the resurrection plant Myrothamnus flabellifolius, 3,4,5 tri-O-galloylquinic acid, protects membranes against desiccation and free radical-induced oxidation

5. In vitro culture of the resurrection plant Haberlea rhodopensis

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