Positron emission tomography/computed tomography in patients with cancer of unknown primary origin

Author:

Lucic S.M.1,Lucic M.A.2,Peter A.1,Jovanovic D.3,Vucaj-Cirilovic V.4

Affiliation:

1. Zavod za nuklearnu medicinu, Institut za onkologiju, Sremska Kamenica

2. Centar za imidžing dijagnostiku, Institut za onkologiju Vojvodine, Sremska Kamenica

3. Klinika za internu onkologiju, Institut za onkologiju Vojvodine, Sremska Kamenica

4. Centar za radiologiju, KC Vojvodine, Novi Sad

Abstract

Cancer of unknown primary origin is not an uncommon clinical state, usually accounting for 2%-7% of all cancer patients. Material and methods: Positron emission tomography and computed tomography (PET/CT) was performed in 17 patients with histologically proven metastatic tumors of unknown primary and negative or inconclusive conventional diagnostic procedures. Results: The study included 17 patients (8 male and 9 female) age from 42 to 76 years. PET / CT has pointed out the probable localization of primary tumors in 10 patients. According histological diagnosis of carcinoma of unknown origin, most common is adenocarcinoma (64.71%). Origin of the primary cancer was found in 72.73% patients with adenocarcinoma 66.67% of respondents with squamocelular carcinoma and 50% of respondents with low differentiated carcinoma. Location of primary cancer was not found in 41.18% of the respondents, including patients with mucinous adenocarcinoma and patients with melanoma. Conclusion: FDG PET/CT demonstrates very good whole-body imaging method in evaluation of patients with unknown primary carcinoma.

Publisher

National Library of Serbia

Subject

General Medicine

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