Clinical implications of biochemical alterations induced by hypothalamic thyrotrophin hormone in elderly people

Abstract

Thyrotrophin releasing hormone (TRH) test has been done in 62 subjects (females, average age 72), in order to analyze the stimulated TSH action, to assess the immediate thyroid reserve and to make the rational parameters of the thyroid function in the elderly. It was concluded that biochemical alterations provoked by application of hypothalamic thyrothropin hormone are very complex, but important for the clinical practice, giving the possibility of assessment of the actual state of the thyroid's function. It is also concluded that the estimation of TRH stimulated TSH in 20th and 60th minute, and T3 and FT4 in 60th minute of the TRH test provides very solid and rational method of thyroid function estimation, as well as the estimation of the thyroid reserve.