Synthesis of 5-azaandrostane-3β, 17β-diol protected at the 17-hydroxyl group-Reference-Cited by-同舟云学术

Synthesis of 5-azaandrostane-3β, 17β-diol protected at the 17-hydroxyl group

Published:2004 Issue:11 Volume:69 Page:861-869
ISSN:0352-5139
Container-title:Journal of the Serbian Chemical Society
language:en
Short-container-title:JSCS

Author:

Pavlovic Vladimir¹,Dabovic Milan²,Martinovic Sasa²,Lorenc Ljubinka³,Kalvoda Jaroslav⁴

Affiliation:

1. Faculty of Chemistry, Belgrade

2. Center for Chemistry, ICTM, Belgrade, Serbia and Montenegro

3. Faculty of Chemistry, Belgrade and Center for Chemistry, ICTM, Belgrade, Serbia and Montenegro

4. Leimgrubenweg, Binningen, Switzerland

Abstract

In the present paper, the preparation of 3?-hydroxy-17?-dimethyl-tert-butylsilyloxy- 5-azaandrostane (15) in fourteen steps is described. B-nor-17-oxoandrost- 5-en-3?-yl acetate (1)1,2 was used as the starting material, which was transformed to the key intermediate of the synthesis, B-nor-17?-dimethyl-tert-butylsilyloxyandrost- 4-en-3?-yl acetate (7).

Publisher

National Library of Serbia

Subject

General Chemistry

Reference1 articles.

1. A synthetic approach towards polyfunctional 5-azasteroids

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