Efficiency of leptin gene polymorphisms in the evaluation of the growth performance and carcass measurements of v-line and Baladi black rabbits
Author:
Radwan Hend1, Ateya Ahmed1, Abo Elfadl1, Sakr Shimaa1, Fouda Mohamed1, Darwish Ragab1, El-Desoky Adel2
Affiliation:
1. Department of Husbandry and Development of Animal Wealth, Faculty of Veterinary Medicine, Mansoura University, Mansoura, Egypt 2. Department of Waterfowls and Rabbits Researches, Animal Production Research Institute, Dokki, Giza, Egypt
Abstract
This study investigated the association between both polymorphisms and
metabolic marker changes of the leptin gene, and body weight, weight gain,
carcass traits, feed intake, and feed conversion ratio. Blood samples were
collected from 60 V-line and 60 Baladi Black rabbits for DNA extraction and
biochemical analysis. DNA sequencing of leptin (202-bp) revealed four
non-synonymous single nucleotide polymorphism (SNPs) that characterized a
number of V-line rabbits. Statistical analysis revealed that the identified
SNPs were associated with rabbit growth and carcass measurements (p < 0.05).
A discriminant analysis model showed a high classification percentage for
the identified SNPs within and between breeds using body weight at 5-14
weeks of age (91.7%), slaughter traits (91.6%), feed intake, daily feed
intake, and feed conversion ratio (76.7%). This study reveals that leptin
gene could be a candidate for growth traits in rabbits enabling the
development of marker-assisted selection (MAS) in different rabbit breeds.
Publisher
National Library of Serbia
Subject
Plant Science,Genetics
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