Waterlogging affects the anti-melanogenic properties of Platycodon grandiflorus roots

Abstract

Waterlogging caused by climate change has threatened the growth and production yield of crops. Although morphological and physiological changes in major crops under waterlogging have been well-defined, the effect of waterlogging on the quality of medicinal plants remains largely unknown. In this study, we analysed waterlogging-induced variations in the anti-melanogenic properties of Platycodon grandiflorus roots. Based on the analysis of melanin production and the expression levels of melanogenic enzymes, we found that waterlogging negatively impacted the anti-melanogenic properties of P. grandiflorus roots. Using UPLC-ESI-Q-TOFMS, we identified 12 compounds including platycodin D3 and platycodin A, which showed differences between untreated and waterlogging-treated roots. In addition, waterlogging led to the suppression of the triterpenoid saponin biosynthetic pathway. Taken together, our results will form an important basis for understanding the impact of climate change on the quality of medicinal plants.