Determination of isotopic distribution of lead by a matrix assisted laser desorption/ionization versus a laser desorption/ionization time of flight mass spectrometry
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Published:2017
Issue:1
Volume:71
Page:19-26
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ISSN:0367-598X
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Container-title:Chemical Industry
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language:en
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Short-container-title:Hem Ind
Author:
Kamceva Tina1,
Nesic Maja2ORCID,
Stoiljkovic Milovan2ORCID,
Popovic Iva2ORCID,
Miletic Jadranka2,
Rajcic Boris2ORCID,
Petkovic Marijana2ORCID,
Velickovic Suzana2ORCID
Affiliation:
1. Haukeland University Hospital, Section of Clinical Pharmacology, Laboratory of Clinical Biochemistry, Bergen, Norway
2. Institute of Nuclear Sciences “Vinča”, Belgrade
Abstract
In this work it has been shown that both the laser desorption/ionization mass
spectrometry (LDI MS) and the matrix assisted laser desorption/ionization
time-of-flight mass spectrometry (MALDI TOF MS) are the simple and quick
methods for determination of relative natural isotopic distribution of lead.
The analysis of metal salts with these approaches does not require any
time-consuming preparation of samples: a single run can take only a minute,
and numerous information can be obtained. Results obtained in this work show
that chosen matrix has no negative effect on quantitative determination of
lead isotopes and support once more the applicability of MALDI TOF MS for
lead isotope distribution determination in the sample, and accuracy of data
obtained. Additionally, the generation of PbnOn and PbnOn-1 (n: 2 - 6)
clusters have been successfully achieved in the positive mode, using the both
LDI and MALDI methods. All stoichiometries were confirmed using isotopic
pattern modelling.
Funder
Ministry of Education, Science and Technological Development of the Republic of Serbia
Publisher
National Library of Serbia
Subject
General Chemical Engineering,General Chemistry