Superoxide dismutase activity as a function of culture aging of B-16 mouse melanoma cells-Reference-Cited by-同舟云学术

Superoxide dismutase activity as a function of culture aging of B-16 mouse melanoma cells

Published:2004 Issue:12 Volume:69 Page:1005-1011
ISSN:0352-5139
Container-title:Journal of the Serbian Chemical Society
language:en
Short-container-title:JSCS

Author:

Radojicic Ratko¹,Spasic Snezana²^ORCID,Saicic Zorica³^ORCID,Jovanovic Tamara⁴,Simic-Krstic Jovana⁴

Affiliation:

1. Institute of Physiology and Biochemistry, Faculty of Biology, Belgrade

2. Center for Chemistry ICTM, Belgrade

3. Institute for Biological Research 'Siniša Stanković', Department of Physiology, Belgrade

4. Fullerene Science and Technology Centre, Chemical Power Sources Institute, Belgrade-Zemun, Serbia and Montenegro

Abstract

The C3 clone of B-16 mouse melanoma was cultured for 1, 6 and 9 days and analyzed. The changes which are not directly linked to melanogenesis in the B-16 / C3 cultures during their maturation were characterized. Early (1 day) confluent (6 days) and old (9 days) cell cultures are distinguished by their leucine aminopeptidase (LAP) and ?-naphthyl acetate esterase (ANAE) isoenzyme patterns. Both quantitative and qualitative changes in LAP and ANAE isoenzyme can be observed during culture maturation. There is an increase in the activity of the enzyme copper, zinc-containing superoxide-dismutase (CuZn SOD). The increaase in the CuZn SOD enzyme activity might be related to B-16/C3 cell melanogenesis and / or to differentiation.

Publisher

National Library of Serbia

Subject

General Chemistry

Reference9 articles.

1. Lipid peroxidation and antioxidant capacity in selected tissues of healthy black C57BL/6J mice and B16 melanoma-bearing mice

2. DISC ELECTROPHORESIS - II METHOD AND APPLICATION TO HUMAN SERUM PROTEINS*

3. Genetic control of multiple molecular forms of enzymes in plants: A review

4. Peroxidase-Mediated Mechanisms Are Involved in the Melanocytotoxic and Melanogenesis-Inhibiting Effects of Chemical Agents

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