Affiliation:
1. Toxicology Laboratory, Department of Applied Zoology, School of Biological Sciences, Jnana Sahyadri, Shankaraghatta, Shimoga, Karnataka, India
Abstract
The present study was conducted to evaluate the effects of zinc cyanide
(Zn(CN)2) on the ATPase (Na+-K+-, Mg2+, Ca2+) activity of the freshwater fish
Cirrhinus mrigala (Ham). Fish were exposed to two sublethal concentrations
(0.114 and 0.068 mg/L) and the effects were studied in the liver, muscle and
gill tissues at the end of 5, 10 and 15 days of exposure. Cyanide
intoxication resulted in marked changes in ATPases, represented by a
significant decrease in the activities. Maximum inhibition was observed at
higher concentration. The order of inhibition in the activity was Na+-K+->
Ca2+ > Mg2+ ATPase. These results imply an immediate adaptive response to the
stress, demonstrating alterations in ATPase activities in the tissues of
cyanide-treated fish. The present study clearly proposes that ATPases can be
used as biomarkers of exposure of aquatic organisms to cyanide intoxication.
Publisher
National Library of Serbia
Subject
General Agricultural and Biological Sciences,General Biochemistry, Genetics and Molecular Biology
Cited by
7 articles.
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