The influence of lead on gingiva and periodontal tissue-Reference-Cited by-同舟云学术

The influence of lead on gingiva and periodontal tissue

Published:2023 Issue:4 Volume:70 Page:189-195
ISSN:0039-1743
Container-title:Stomatoloski glasnik Srbije
language:en
Short-container-title:Stomatol glas Srb

Author:

Kuzmanovic-Radman Irena¹,Arbutina Adriana²^ORCID,Josipovic Renata¹,Marin Sasa³^ORCID,Umicevic-Davidovic Mirjana²,Arbutina Radmila¹,Trtic Natasa⁴,Protic-Beric Verica⁵,Djeri Aleksandra¹

Affiliation:

1. University of Banja Luka, Faculty of Medicine, Department of Dental Diseases, Banja Luka, Republika Srpska, Bosnia and Herzegovina

2. University of Banja Luka, Faculty of Medicine, Department of Jaw Orthopedics, Banja Luka, Republika Srpska, Bosnia and Herzegovina

3. University of Banja Luka, Faculty of Medicine, Department of Oral Surgery, Banja Luka, Republika Srpska, Bosnia and Herzegovina

4. University of Banja Luka, Faculty of Medicine, Department of Periodontology and Oral Medicine, Banja Luka, Republika Srpska, Bosnia and Herzegovina

5. ZU „Prizma Dent“, Banja Luka, Bosnia and Herzegovina

Abstract

Introduction. Exposure to lead (Pb) can have harmful effects on the general state of the body, including oral health. The aim of this study was to examine the prevalence of changes in gingiva and periodontal tissue in adult rats intoxicated with lead acetate by histological analysis. Material and methods. The study was conducted on 42 Wistar rats. Intoxication of rats with lead acetate was carried out through drinking water ad libitum. The first group (A1) consisted of 16 rats that received lead-acetate in water at a concentration (1500 ppm) for 14 days, and the second group (A2) consisted of 16 rats that received lead-acetate in water at the same concentration for 30 days. Results. Gingivitis and periodontitis in the first group of rats (A1) were observed in 41.7% of cases, and in the second group (A2) in 84% of cases. A statistically significant difference was found between the investigated groups (?2 = 6.955; p < 0.018). Conclusion. Since changes in the gingiva and periodontium have been observed in rats intoxicated with lead for a long period of time, it is necessary to propose a preventive program for patients exposed to lead, which includes dental procedures such as oral hygiene training and regular visits to the dentist.

Publisher

National Library of Serbia

Reference30 articles.

1. Tinkov AA, Filippini T, Ajsuvakova OP, Skalnaya MG, Aaseth J, Bjørklund G, et al. Cadmium and atherosclerosis: a review of toxicological mechanisms and a meta-analysis of epidemiologic studies. Environ Res. 2018;162:240-60. [DOI: 10.1016/j.envres.2018.01.008] [PMID: 29358116]

2. Mehrotra N, Singh S. Periodontitis. In: StatPearls. StatPearls Publishing, Treasure Island (FL); 2022. [DOI: //www.ncbi.nlm.nih.gov/books/NBK541126/]

3. Kamberi B, Koçani F, Dragusha E. Teeth as Indicators of Environmental Pollution with Lead. J Environment Analytic Toxicol. 2012;2:1-5. [DOI: 10.4172/2161-0525.1000118]

4. Yetkin-Ay Z, Cadir B, Uskun E, Bozkurt FY, Delibas N, Gultepe FM, et al. The periodontal status of indirectly lead-exposed apprentices working in autorepair workshops. Toxicol Ind Health. 2007;23(10):599-606. [DOI: 10.1177/0748233708090906] [PMID: 18717518]

5. Chakraborty S, Tewari S, Sharma RK, Narula SC, Ghalaut PS, Ghalaut V. Impact of iron deficiency anemia on chronic periodontitis and superoxide dismutase activity: a cross-sectional study. J Periodontal Implant Sci. 2014;44(2):57-64. [DOI: 10.5051/jpis.2014.44.2.57] [PMID: 24778899]