Adverse events associated with donor plateletpheresis: 10 years’ experience from Vojvodina, Serbia
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Published:2021
Issue:00
Volume:
Page:21-21
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ISSN:0042-8450
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Container-title:Vojnosanitetski pregled
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language:en
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Short-container-title:VOJNOSANIT PREGL
Author:
Budakov-Obradovic Zorana1,
Bujandric Nevenka1,
Grujic Jasmina1ORCID
Abstract
Background/Aim. Plateletpheresis is a medical procedure used for the
collection of donor platelets with multiple benefits for patients who will
receive apheresis platelets. The procedure takes one hour and is well
tolerated by donors. Nevertheless, adverse events may occur during and after
the plateletpheresis procedure. The aim was to present one centre
experiences in order to determine the incidence and type of adverse events
associated with donor plateletpheresis. Methods. A retrospective analysis of
adverse events associated with donor plateletpheresis was conducted in the
Blood Transfusion Institute of Vojvodina over the period from January 1,
2010 through December 31, 2019. Results. Out of 2073 platelet donors 94.84%
were multiple blood donors, predominantly male (98.55%). Adverse events were
identified during 180 (8.68%) platelet donations with no statistical
significance in occurrence in the first time (10.28%) and repeat donors
(8.59%). Mild local reactions related to venous access (42.22%) were the
most common adverse events. Generalized symptoms exhibited 16.67% of donors,
26.11% exhibited symptoms related to apheresis - citrate reactions and 15%
exhibited those related to other complications. During plateletpheresis
occurred 95.55% adverse events and 4.45% after. Conclusion. Donor
plateletpheresis is a generally safe procedure, well tolerated by donors.
Understanding risk factors for possible occurrence of adverse events provide
support for adoption of measures to prevent them.
Publisher
National Library of Serbia
Subject
Pharmacology (medical),General Medicine