The chemical composition, antimicrobial and antioxidant activities of the essential oil of Salvia fruticosa growing wild in Libya

Author:

Giweli Abdulhamid1,Dzamic Ana2ORCID,Sokovic Marina3,Ristic M.S.4,Janackovic P.2,Marin P.D.2

Affiliation:

1. Faculty of Biology, Institute of Botany and Botanical Garden “Jevremovac”, Belgrade + Department of Botany, Faculty of Science, University of Al-Gabel Al-Garbe, Zintan, Libya

2. Faculty of Biology, Institute of Botany and Botanical Garden “Jevremovac”, Belgrade

3. Institute for Biological Research “Siniša Stanković”, Belgrade

4. Institute for Medicinal Plant Research “Dr Josif Pančić”, Belgrade

Abstract

The composition of essential oil isolated from Salvia fruticosa, wild growing in Libya, was analyzed by GC and GC-MS. Forty-five compounds could be identified. The essential oil contained 1,8-cineole (49.34%), camphor (7.53%), ?-pinene (7.38%), myrcene (7.38%), ?-pinene (5.15%), ?-caryophyllene (4.13%) and ?-terpineol (3.25). Antioxidant activity was analyzed using the DPP H free radical scavenging method and low antioxidant activity was found (IC50 = 15.53 mg/ml). The oil was also screened for its antimicrobial activity against eight bacteria (four Gram-negative and four Gram-positive) and eight fungi. The essential oil of S. fruticosa showed minimal inhibitory activity (MIC) at 0.125-1.5 mg/ml and bactericidal (MBC) at 0.5-2.0 mg/ml. In addition, it exhibited fungistatic (MIC) at 0.125-1.0 mg/ml and fungicidal effect (MFC) at 0.125-1.5 mg/ml.

Funder

Ministry of Education, Science and Technological Development of the Republic of Serbia

Publisher

National Library of Serbia

Subject

General Agricultural and Biological Sciences,General Biochemistry, Genetics and Molecular Biology

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