A recently published study further advances the drive toward precision medicine in IVF

Author:

Gleicher Norbert1234ORCID

Affiliation:

1. Center for Human Reproduction (CHR), New York, NY

2. Foundation for Reproductive Medicine, New York, NY

3. Stem Cell and Embryology Laboratory, Rockefeller University, New York, NY

4. Medical University of Vienna, Vienna, Austria

Abstract

The individualized timing of ovulation triggers to such very small follicle sizes and, therefore, at times extremely early egg retrieval, significantly shortens IVF cycles and mandates very close, daily observation of patients. That MII oocytes with advancing female age lose ability to produce good-quality embryos is, of course, also a potentially almost revolutionary finding because practically every IVF cycle in the world currently strives to maximize the percentage of MII oocytes in every IVF cycle’s egg-cohort.

Publisher

SAABRON PRESS

Reference6 articles.

1. Aging-related premature luteinization of granulosa cells is avoided by early oocte retrieval;Y.-G. Wu;Endocrinol,2015

2. With low ovarian reserve, Highly Individualized Egg Retrieval (HIER) improves IVF results by avoiding premature luteinization;Yan-Guang Wu;Journal of Ovarian Research,2018

3. Older women using their own eggs? Issue framed with two oldest reported IVF pregnancies and a live birth;Norbert Gleicher;Reproductive BioMedicine Online,2018

4. Rescue in vitro maturation of immature oocytes in stimulated cycles in women with low functional ovarian reserve (LFOR);H.-J. Lee;Endocrine,2016

5. How to identify patients who would benefit from delayed-matured oocytes insemination: a sibling oocyte and ploidy outcome study;I Elkhatib;Human Reproduction,2023

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