Metformin Reduces the Progression of Atherogenesis by Regulating the Sestrin2-mTOR Pathway in Obese and Diabetic Rats

Author:

Sundararajan Saravanakumar1ORCID,Jayachandran Isaivani12ORCID,Pandey Gautam Kumar1ORCID,Venkatesan Saravanakumar1ORCID,Rajagopal Anusha1ORCID,Gokulakrishnan Kuppan3ORCID,Balasubramanyam Muthuswamy4ORCID,Mohan Viswanathan5ORCID,Manickam Nagaraj1ORCID

Affiliation:

1. Department of Vascular Biology, Madras Diabetes Research Foundation & ICMR Centre for Advanced Research on Diabetes, Chennai, India.

2. Department of Biotechnology, Sri Venkateswara College of Engineering, Sriperumbudur, India.

3. Department of Neurochemistry, National Institute of Mental Health and Neurosciences (NIMHANS), Hosur Road, Bengaluru, India.

4. Department of Cell and Molecular Biology, Madras Diabetes Research Foundation & ICMR Centre for Advanced Research on Diabetes, Chennai, India.

5. Madras Diabetes Research Foundation and Dr. Mohan’s Diabetes Specialities Centre, Chennai, India.

Funder

Madras Diabetes Research Foundation

Publisher

XMLink

Subject

Cardiology and Cardiovascular Medicine,Endocrinology, Diabetes and Metabolism,Internal Medicine

Reference22 articles.

1. The Metabolic Syndrome

2. Metabolic syndrome: definitions and controversies

3. World Health Organization. Obesity and overweight [Internet]. Geneva. World Health Organization. 2021. cited 2023 Jun 9. Available from: https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight

4. Mechanism of Development of Atherosclerosis and Cardiovascular Disease in Diabetes Mellitus

5. Atherosclerosis

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