<i>In silico</i> Analysis of Interactions between <i>HLA-A*31:01</i> and carbamazepine-related Compounds-Reference-Cited by-同舟云学术

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In silico Analysis of Interactions between HLA-A*31:01 and carbamazepine-related Compounds

Published:2016 Issue:0 Volume:16 Page:5-8
ISSN:1347-0442
Container-title:Chem-Bio Informatics Journal
language:en
Short-container-title:CBIJ

Author:

Miyadera Hiroko¹²,Ozeki Takeshi³,Mushiroda Taisei³,Hirayama Noriaki⁴

Affiliation:

1. Department of Human Genetics, Graduate School of Medicine, The University of Tokyo

2. Research Center for Hepatitis and Immunology, National Center for Global Health and Medicine

3. Laboratory for Pharmacogenomics, RIKEN Center for Integrative Medical Sciences

4. Institute of Advanced Biosciences, Tokai University

Publisher

Chem-Bio Informatics Society

Subject

Biochemistry

Link

https://www.jstage.jst.go.jp/article/cbij/16/0/16_5/_pdf

Reference14 articles.

1. [1] Ozeki, T.; Mushiroda, T.; Yowang, A.; Takahashi, A.; Kubo, M.; et al. Genome-wide association study identifies HLA-A*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population. Hum. Mol. Genet. 2011, 20, 1034-1041.

2. [2] Pichler, W. J.; Adam, J.; Watkins, S.; Wuillemin, N.; Yun, J.; et al. Drug Hypersensitivity: How Drugs Stimulate T Cells via Pharmacological Interaction with Immune Receptors. Int. Arch. Allergy Immunol. 2015, 168, 13-24.

3. [3] Lichtenfels, M.; Farrell, J.; Ogese, M. O.; Bell, C. C.; Eckle, S.; et al. HLA restriction of carbamazepine-specific T-Cell clones from an HLA-A*31:01-positive hypersensitive patient. Chem. Res. Toxicol. 2014, 27, 175-177.

4. [4] Illing, P. T.; Vivian, J. P.; Dudek, N. L.; Kostenko, L.; Chen, Z. et al. Immune self-reactivity triggered by drug-modified HLA-peptide repertoire. Nature, 2012, 486, 554-558.

5. [5] Kim, K. A.; Oh, S. O.; Park, P. W.; Park, J. Y. Effect of probenecid on the pharmacokinetics of carbamazepine in healthy subjects. Eur J Clin Pharmacol. 2005, 61, 275-280.

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1. Docking simulations between drugs and HLA molecules associated with idiosyncratic drug toxicity;Drug Metabolism and Pharmacokinetics;2017-02

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