Biomolecular Chemical Simulations toward Elucidation of the Enantioselectivity and Reactivity of Lipases in Organic Synthesis
Author:
Affiliation:
1. Department of Electrical and Electronic Engineering, Okayama University of Science
2. Konan Chemical Industry Co., Ltd.
3. Research Institute of Natural Sciences, Okayama University of Science
Publisher
Chem-Bio Informatics Society
Subject
Biochemistry
Link
https://www.jstage.jst.go.jp/article/cbij/18/0/18_21/_pdf
Reference19 articles.
1. [1] Naoshima, Y.; Munakata, Y.; Yoshida, S.; Funai, A. Synthesis of Chiral Alcohol and Ester Pheromones through Enzyme-Catalysed Hydrolysis using Pseudomonas fluorescens Lipase: Preparation of (2R,6S,10S)-6,10-14-Trimethylpentadecan-2-ol and the Propionate of (2R,8R)-8-methyldecan-2-ol. J. Chem. Soc., Perkin Trans. 1. 1991, 549-553.
2. [2] Naoshima, Y.; Kamezawa, M.; Tachibana, H.; Munakata, Y.; Fujita, T.; et al. Enzymatic Preparation of Enantiomerically Pure Alkan-2- and -3-ols by Lipase-Catalysed Hydrolysis with Pseudomonas cepacia in the Presence of Organic Media. J. Chem. Soc., Perkin Trans. 1. 1993, 557-561.
3. [3] Ohtani, T.; Nakatsukasa, H.; Kamezawa, M.; Tachibana, H.; Naoshima, Y. Enantioselectivity of Candida antarctica lipase for some synthetic substrates including aliphatic secondary alcohols. J. Mol. Catal. B: Enzym. 1998, 4(1-2), 53-60.
4. [4] Naoshima, Y.; Kamezawa, M.; Kimura, T.; Okimoto, F.; Watanabe, M.; et al. Enantioselectivity and reactivity of Candida and Pseudomonas sp. lipases for synthetic substrates: Biocatalytic synthesis of chiral building blocks with alkanol skeletons. Recent Res. Devel. Org. Bioorg. Chem. 2001, 4, 1-16.
5. [5] Kamori, M.; Yamashita, Y.; Naoshima, Y. Enzyme Immobilization Utilizing a Porous Ceramics Support for Chiral Synthesis. CHIRALITY 2002, 14(7), 558-561.
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