Abstract
Two enantiomerically pure products, (+)-biotin and dextromethorphan, have been chosen to illustrate the acquisition, development, and implementation of the catalytic asymmetric hydrogenation technology at Lonza Fine Chemicals. Taking advantage of the recently developed Ciba-Geigy ferrocenyl-type phosphine ligands, processes for the stereoselective hydrogenation of a C=C- and a C=N bond, respectively, have been developed and successfully scaled up.
Subject
General Medicine,General Chemistry
Cited by
3 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献