Comparison of Clinical Symptoms and Severity of Sleep Disordered Breathing in Children with and without Cleft Lip and/or Palate

Author:

Maclean Joanna E1,Fitzsimons David2,Fitzgerald Dominic3,Waters Karen3

Affiliation:

1. Division of Respiratory Medicine, Department of Pediatrics, University of Alberta, Edmonton, AB, Canada. David Fitzsimons is Speech Pathologist, Discipline of Paediatrics & Child Health, Physiology University of Sydney, Sydney, NSW, Australia, and Speech Pathologist, Cleft Palate Clinic, The Children's Hospital at Westmead, Westmead, NSW, Australia.

2. Professor, Discipline of Paediatrics & Child Health, University of Sydney, Sydney, NSW, Australia, and Pediatric Respiratory Physician, Department of Respiratory Medicine, The Children's Hospital at Westmead, Westmead, NSW, Australia;

3. Discipline of Paediatrics & Child Health, and Department of Physiology University of Sydney, and Pediatric Respiratory Physician, The Children's Hospital at Westmead, Westmead, NSW, Australia.

Abstract

Objective To determine whether the clinical presentation or severity of sleep disordered breathing differs between children with or without a history of cleft lip and/or palate (CL/P) presenting for sleep assessment. Design Retrospective chart review. Setting Tertiary care pediatric hospital cleft clinic, sleep clinic. Patients Children > 6 months of age presenting to the cleft clinic with sleep concerns and children without CL/P presenting to the sleep clinic in the same 2-year period. Main Outcomes Measures Clinical symptoms and overnight polysomnography (PSG) results. Results A total of 168 children (55 from cleft clinic, 113 from sleep clinic) were identified. Age at clinical review (6.6 ± 4.1 years versus 6.8 ± 4.0 years, P = ns), sex distribution (64.6% versus 58.4%, P = ns), and the presence of syndromes or significant medical conditions (12% versus 16%, P = ns) were similar between groups. Snoring was the reason for referral in 59% of children with CL/P and 69% of non-CL/P children ( P = ns). The only presenting feature that differentiated between the groups was a lower incidence of tonsillar enlargement in children with CL/P (33% versus 79%, chi-square 30.4, P < 0.001). Sleep study results showed similar apnea-hypopnea indices (6.2 ± 6.9 versus 7.9 ± 7.1 events/hr, P = ns) with more central apnea in children with CL/P (1.5 ± 1.5 versus 1.0 ± 1.0 events/hr, P = 0.017). Conclusions Snoring and obstructive sleep apnea are common in CL/P with less tonsillar enlargement than non-CL/P children. Children with CL/P have similar OSA severity compared to non-cleft children but more central apnea which may indicate differences in the control of breathing.

Publisher

SAGE Publications

Subject

Otorhinolaryngology,Oral Surgery

Reference49 articles.

1. Robin Sequence: Obstructive Sleep Apnea following Pharyngeal Flap

2. Snoring, sleep disturbance, and behaviour in 4-5 year olds.

3. Activity-Adjusted 24-Hour Ambulatory Blood Pressure and Cardiac Remodeling in Children with Sleep Disordered Breathing

4. Australasian Sleep Association, ASTA/ASA addendum to AASM Guidelines for recording and scoring paediatric sleep, April 2011. Available at http://www.sleep.org.au/documents/item/218. Accessed November 14, 2015.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3