Microbiological , Antimicrobile Profile and Antibiotic Resistance of Urinary System Infections in Children in Usak

Abstract

Background: Urinary tract infection (UTI) is one of the most common pediatric infections, accounting for 3% of all infections among the pediatric population and affect 2% of males and 8% of females by age seven. Bacteria are the common etiology of UTIs, accounting for over 95% of cases. Escherichia coli is the most common causative organism of UTI. Antibiotics are included in the treatment of these infections. Therefore, determining the correct antibiotic susceptibility is essential in the clinical care of bacterial infections. Bacteria that have the potential to develop resistance to antibiotics need to be monitored more closely. Methods: A total of 1250 urine culture results were retrospectively analyzed from pediatric patients aged 0–16 years who were admitted to Usak Oztan Hospital as outpatients with symptoms and complaints of urinary tract infection and whose urine analysis and urine culture were taken between January 2018 and December 2020. Result: Gram-negative microorganism growth was found in 238 (19%) of the 1250 pediatric patients evaluated in our study. There was no growth in the urine cultures of 877 (70%) patients. E. coli was the most isolated microorganism in our study, which was detected in 168 (70.5%) of the patients. Conclusions: We present the first antimicrobial resistance data for the city of Usak. Our study showed that amoxicillin/clavulanate is not the best option for empirical treatment of community acquired UTIs, contrary to current local practice. In addition, ceftriaxone was found to be the second most resistant antibiotic in our study.