The correlation of C-reactive protein/albumin, MII-1 and MII-2 indexes with hospitalization and mortality in acute dissection

Abstract

Objective: In this study we aimed to investigate the relationship between CRP/albumin ratio, MII-1 and MII-2 indexes in hospitalization and mortality due to aortic dissection. Methods: Patients who presented to our emergency department with a sudden-onset, sharp and stabbing chest pain and diagnosed with acute aortic dissection were included in the study. Patients' demographics such as age and gender, hemogram parameters, ratios, indexes, hospitalization and mortality status were recorded. Demographic features, hemogram parameters, ratios and indexes were compared between the survivor and exitus patients. Results: A total of 71 patients who presented to the emergency department with sudden-onset stabbing chest pain and subsequently diagnosed with aortic dissection were included in this retrospective study. Median age was negatively correlated with hemoglobin (r=-0.28, p=0.019), albumin (r=-0.27, p=0.021) and prognostic nutritional index (PNI) (r=-0.31, p=0.008). Hemoglobin values were significantly higher in male than in female patients. The median length of stay in the hospital was found as 10 (7-14) days. In the correlation analysis of the hemogram parameters, indexes and length of stay in the hospital; CRP and CRP/ALB ratio were significantly correlated with length of stay in the hospital in positive direction (Table 3). Conclusion: The results of this study point out a significant correlation between CRP, CRP/albumin ratio and length of stay in hospital. This information might be helpful in rapid decision making process for early diagnosis and treatment of the disease