Bone Regeneration by Low-dose Recombinant Human Bone Morphogenetic Protein-2 Carried on Octacalcium Phosphate Collagen Composite

Author:

Bien Nguyen Dien1,Miura Kei-ichiro1,Sumita Yoshinori2,Nakatani Yuya1,Shido Rena1,Kajii Fumihiko3,Kamakura Shinji4,Asahina Izumi1

Affiliation:

1. Department of Regenerative Oral Surgery, Nagasaki University Graduate School of Biomedical Sciences

2. Basic and Translational Research Center for Hard Tissue Disease, Nagasaki University Graduate School of Biomedical Sciences

3. TOYOBO Co., Ltd., Medical Equipment & Devices Production Center

4. Division of Bone Regenerative Engineering, Tohoku University Graduate School of Biomedical Engineering

Publisher

Society for Hard Tissue Regenerative Biology

Subject

Cell Biology,General Dentistry,Orthopedics and Sports Medicine,Biomaterials,Biochemistry,Medicine (miscellaneous)

Reference30 articles.

1. 1. LeGeros RZ. Properties of osteoconductive biomaterials: calcium phosphates. Clin Orthop Relat Res 395: 81-98, 2002

2. 2. Ogose A, Hotta T, Kawashima H, Kondo N, Gu W, Kamura T and Endo N. Comparison of hydroxyapatite and beta tricalcium phosphate as bone substitutes after excision of bone tumors. J Biomed Mater Res B Appl Biomater 72: 94-101, 2005

3. 3. Ogose A, Kondo N, Umezu H, Hotta T, Kawashima H, Tokunaga K, Ito T, Kudo N, Hoshino M and Gu W. Histological assessment in grafts of highly purified beta-tricalcium phosphate (OSferion®) in human bones. Biomaterials 27: 1542-1549, 2006

4. 4. Lichte P, Pape HC, Pufe T, Kobbe P and Fischer H. Scaffolds for bone healing: concepts, materials and evidence. Injury 42: 569-573, 2011

5. 5. Asahina I. Bone morphogenetic proteins: their history and characteristics. J Hard Tissue Biol 23: 283-286, 2014

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