Curcumin Enhances the Anticancer Effects of Binimetinib on Melanoma Cells by Inducing Mitochondrial Dysfunction and Cell Apoptosis with Necroptosis

Author:

Lee Yoon Jin12ORCID,Heo Jae Young3ORCID,Kim Dong Sung3ORCID,Choi Yu Sung3ORCID,Kim Sooyoung3ORCID,Nam Hae Seon2ORCID,Lee Sang Han1ORCID,Cho Moon Kyun3ORCID

Affiliation:

1. Department of Biochemistry, Soonchunhyang University College of Medicine, Cheonan, Korea.

2. Division of Molecular Cancer Research, Soonchunhyang Medical Research Institute, Soonchunhyang University, Cheonan, Korea.

3. Department of Dermatology, Soonchunhyang University Seoul Hospital, Seoul, Korea.

Funder

Soonchunhyang University

Publisher

XMLink

Subject

Dermatology

Reference51 articles.

1. Cancer statistics, 2022

2. National Cancer Institute. Cancer stat facts: melanoma of the skin [Internet]. National Cancer Institute. 2022. cited 2022 Oct 22. Available from: https://seer.cancer.gov/statfacts/html/melan.html

3. Insights into the Transforming Growth Factor-β Signaling Pathway in Cutaneous Melanoma

4. Prognostic and Clinicopathologic Associations ofBRAFMutation in Primary Acral Lentiginous Melanoma in Korean Patients: A Preliminary Study

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