1. a Department of Biostatistics and Data Management , Aventis Pharmaceuticals, Inc. , Mail Stop BX2-400C, Bridgewater, NJ, 08807, U.S.A.
2. b Office of Biostatistics, OPass, CDER, Food and Drug Administration , Room 15B45, 5600 Fishers Lane, Rockville, MD, 20857, U.S.A.