1. a Department of Health Care Policy , Harvard Medical School , 180 Longwood Avenue, Boston, MA, 02115, U.S.A.
2. b Department of Health Care Policy , Harvard Medical School, and Department of Biostatistics, Harvard School of Public Health , Boston, Massachusetts, USA, U.S.A.
3. c Divisions of Clinical Biometrics and Cardiovascular Disease, Department of Medicine , Brigham and Women's Hospital, Harvard Medical School , Boston, Massachusetts, USA, U.S.A.