Olefin Cross‐Metathesis: A Powerful Tool for Constructing Vaccines Composed of Multimeric Antigens
Author:
Publisher
Informa UK Limited
Subject
Organic Chemistry,Biochemistry
Link
http://www.tandfonline.com/doi/pdf/10.1080/10256018808623883
Reference46 articles.
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3. Livingston, P. and Ragupathi, G. (1997) Carbohydrate vaccines that induce antibodies against cancer. 2. Previous experience and future plans Cancer Immunol. Immunother., 45, pp. 10 - 19.
4. Ragupathi, G. and Slovin, S. and Adluri, S. and Sames, D. and Kim, I.‐J. and Kim, H. and Spassova, M. and Bornmann, W. and Lloyd, K. and Scher, H. and Livingston, P. and Danishefsky, S. (1999) A fully synthetic globo H carbohydrate vaccine induces a focused humoral response in prostate cancer patients: a proof of principle Angew. Chem. Int. Ed., 38, pp. 563 - 566. For the results of phase I clinical trials, see:
5. Slovin, S. and Ragupathi, G. and Adluri, S. and Ungers, G. and Terry, K. and Kim, S. and Spassova, M. and Bornmann, W. and Fazzari, M. and Danits, L. and Olkiwicz, K. and Lloyd, K. and Livingston, P. and Danishefsky, S. and Scher, H. (1999) Carbohydrate vaccines in cancer: immunogenicity of a fully synthetic globo H hexasaccharide conjugate in man Proc. Nat. Acad. Sci. USA,, 96, pp. 5710 - 5715.
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