1. a Graduate School of Pharmaceutical Sciences , Nagasaki, 852-8521, Japan
2. b School of Pharmaceutical Sciences, Nagasaki University , Nagasaki, 852-8521, Japan
3. c National Institute of Health Sciences , 1-18-1, Kamiyoga, Setagaya-Ku, Tokyo, 158-8501, Japan
4. d Graduate School of Pharmaceutical Sciences , Nagasaki, 852-8521, Japan