LARGE-SCALE SYNTHESIS OF 5′-O-PIXYL PROTECTED 2′-DEOXYNUCLEOSIDES USEFUL FOR OLIGONUCLEOTIDE SYNTHESIS
Author:
Affiliation:
1. a RI Chemical, Inc. , Orange, California, USA
2. b Rasayan Inc. , Encinitas, California, USA
Publisher
Informa UK Limited
Subject
Genetics,Molecular Medicine,Biochemistry,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1081/NCN-200065966
Reference7 articles.
1. Studies on Polynucleotides. XXIV.1 The Stepwise Synthesis of Specific Deoxyribopolynucleotides (4).2 Protected Derivatives of Deoxyribonucleosides and New Syntheses of Deoxyribonucleoside-3″ Phosphates3
2. The 9-phenylxanthen-9-yl protecting group
3. A General Approach to the Chemical Synthesis of Oligodeoxyribonucleotides.
4. The pixyl (Px) group: A novel photocleavable protecting group for primary alcohols
5. Alternatives to the 4,4′-dimethoxytrityl (DMTr) protecting group
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2. Regioselective 2,7-dimethyl-9-phenyl xanthen-9-yl protection and deprotection of nucleosides under mild conditions;Tetrahedron Letters;2023-05
3. Renewable amberlyst-15 catalyzed highly regioselective tritylation and deprotection of sugar-based diols;Journal of Carbohydrate Chemistry;2018-06-13
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5. Double-headed nucleotides in DNA-zipper structures; base–base interactions and UV-induced cross-coupling in the minor groove;RSC Adv.;2013
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