TOWARDS A UNIFYING MECHANISM FOR CYP17 MUTATIONS THAT CAUSE ISOLATED 17, 20-LYASE DEFICIENCY
Author:
Publisher
Informa UK Limited
Subject
Endocrinology,General Medicine
Link
http://www.tandfonline.com/doi/pdf/10.1081/ERC-120016821
Reference8 articles.
1. Pitfalls in Characterizing P450c17 Mutations Associated with Isolated 17,20-Lyase Deficiency
2. Improved method for high efficiency transformation of intact yeast cells
3. Cytochrome b 5 Augments the 17,20-Lyase Activity of Human P450c17 without Direct Electron Transfer
4. The genetic and functional basis of isolated 17,20–lyase deficiency
5. P450c17 Mutations R347H and R358Q Selectively Disrupt 17,20-Lyase Activity by Disrupting Interactions with P450 Oxidoreductase and Cytochrome b5
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