ROLE OF LIPOPOLYSACCHARIDE IN DEVELOPMENT OF SEPSIS (REVIEW)

Author:

Хомякова Татьяна Ивановна,Рябинина Ольга Михайловна

Abstract

Липополисахариды грамотрицательных бактерий (LPS) считаются наиболее иммуногенными бактериальными компонентами, ассоциированными с развитием системного воспаления и сепсиса. В обзоре описываются механизмы действия LPS на основные органы-мишени,- легкие, сердце и головной мозг тяжелое поражение которых ассоциировано с развитием дыхательной и сердечной недостаточности. Gram-negative bacterial lipopolysaccharides (LPS) are considered to be the most immunogenic bacterial components associated with the development of systemic inflammation and sepsis. The review describes the mechanisms of action of LPS on the main target organs - the lungs, heart and brain, the severe damage of which is associated with the development of respiratory and heart failure.

Publisher

Crossref

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