THE SAFFRON EFFECTS ON THE DYNAMICS OF EXPERIMENTAL EPILEPSY

Abstract

The scientific work is devoted to the influence of saffron extract on the dynamics of the formation of experimental epilepsy. The dynamics of amygdala-like epileptogenesis created by penicillin sodium salt has been studied, with the registration of electrical activity in the structures of the visual system. The exsperiments was carried out on rabbits. The electrical activity of the structures of the visual system was registered by electroencephalography. Recorded electrical activity of the brain in the central and subcortical structures of the visual analyzer (visual cortex, colliculus superior, lateral geniculata body) normally, as well as against the background of the development of epilepsy. As a result of the research, it was found that the introduction of penicillin solution into the amygdala of animals led to the development of prolonged convulsive activity. To determine the effect of saffron extract on the dynamics of amygdala epileptogenesis, a comparative analysis of the dynamics of epilepsy in control and saffron-treated animals was performed based on several parameters. The results obtained give reason to speak about the presence of the effect of the clarifying effect of saffron on the dynamics of epileptogenesis.