Investigating Differences Between Virulence Factors of Escherichia coli and Pseudomonas aeruginosa in Causing Urinary Tract Infections
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Published:2023-02-14
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ISSN:2693-2326
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Container-title:International Journal of Infectious Diseases and Research
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language:
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Short-container-title:I J Infectious Disea
Abstract
Although the urinary tract (UT) of healthy individuals was traditionally considered sterile, we now know that bacteria persist in the UT of healthy humans. Moreover, bacteriophages are abundant in healthy human TU and probably play a role in modulating the diversity and relative abundance of bacteria within the community. Understanding the urinary microbiota of healthy people has helped us understand the symptoms and diseases of UT in humans. Pseudomonas aeroginosa and Escherichia coli are ubiquitous microorganisms, which is present in diverse environmental. P. aeruginosa and E.coli an increasingly problematic drug-resistant bacterium in today’s world. Uropathogenic Escherichia coli (UPEC) and Pseudomonas aeroginosa express a multitude of virulence factors, which enable the bacteria to establish UTI.
Publisher
Uniscience Publishers LLC
Subject
Pharmacology (medical),Complementary and alternative medicine,Pharmaceutical Science
Reference28 articles.
1. Lin, W. H., Wang, M. C., Liu, P. Y., Chen, P. S., Wen, L. L., Teng, C. H. & Kao, C. Y. (2022). Escherichia coli urinary tract infections: Host age-related differences in bacterial virulence factors and antimicrobial susceptibility. Journal of Microbiology, Immunology and Infection, 55(2), 249- 256. DOI: https://doi.org/10.1016/j.jmii.2021.04.001 2. Wang, M. C., Tseng, C. C., Chen, C. Y., Wu, J. J. & Huang, J. J. (2002). The role of bacterial virulence and host factors in patients with Escherichia coli bacteremia who have acute cholangitis or upper urinary tract infection. Clin Infect Dis, 35(10), 1161-6. DOI: https://doi.org/10.1086/343828 3. Sabharwal, N., Dhall, S., Chhibber, S. & Harjai, K. (2014). Molecular detection of virulence genes as markers in Pseudomonas aeruginosa isolated from urinary tract infections. Int J Mol Epidemiol Genet, 5(3), 125-134. Retrieved from https://pubmed.ncbi.nlm.nih. gov/25379131/ 4. Pearson, J. P., Passador, L., Iglewski, B. H. & Greenberg, E. P. (1995). A second N-acyl-L-homoserine lactone signal produced by Pseudomonas aeruginosa. Proc Natl Acad Sci U S A, 92(5), 1490-1494. DOI: https://doi.org/10.1073/pnas.92.5.1490 5. Winson, M. K., Camara, M., Latifi, A., Foglino, M., Chhabra, S. R., Daykin, M., Bally, M., Chapon, V., Salmond, G. P. & Bycroft, B. W. (1995). Multiple N-acyl-L-homoserine lactone signal molecules regulate production of virulence determinants and secondary metabolites in Pseudomonas aeruginosa. Proc Natl Acad Sci U S A, 92(20), 9427-9431. DOI: https://doi.org/10.1073/pnas.92.20.9427
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