Translation of Electrocardiography and Genetics in Arrhythmogenic Left Ventricular Cardiomyopathy
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Published:2024-06-03
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ISSN:2998-4513
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Container-title:International Journal of Cardiology and Cardiovascular Disorder
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language:
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Short-container-title:IJCCD
Abstract
Translational cardiology combines different techniques in order to get a correct diagnosis (precision medicine). In a rare disease called arrhythmogenic left ventricular cardiomyopathy caused by non-desmosonal gene mutations 12-lead ECG and results of genetics were combined and analyzed. In a few gene mutations ECG findings were highly specific and predicts gene mutation, like desmoplakin, phospholamban, desmoglein-2, desmocollin-2, TMEM43, lamin A/C, and probably filamin C mutation.
With the help of simple 12-lead ECG technique a precise prediction of specific gene mutation can be made.
Publisher
Uniscience Publishers LLC
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