PROGNOSTIC ROLE OF MOLECULAR SUBTYPES OF COLON CANCER. A CURRENT VIEW ON THE PROBLEM-Reference-Cited by-同舟云学术

PROGNOSTIC ROLE OF MOLECULAR SUBTYPES OF COLON CANCER. A CURRENT VIEW ON THE PROBLEM

Published:2021-06-29 Issue:3 Volume:20 Page:107-114
ISSN:2312-3168
Container-title:Siberian journal of oncology
language:
Short-container-title:Sib. onkol. ž.

Author:

Sinyansky L. E.¹^ORCID,Vtorushin S. V.²^ORCID,Patalyak S. V.²^ORCID,Afanasyev S. G.¹^ORCID

Affiliation:

1. Cancer Research institute, Тomsk National Research Medical Center, Russian Academy of Sciences

2. Cancer Research institute, Тomsk National Research Medical Center, Russian Academy of Sciences; Siberian State Medical University

Abstract

Purpose of the study: to review the available data on the heterogeneity of colon cancer and to assess the prognostic significance of colon cancer subtypes.Material and Methods. Medline, PubMed, Cochrane library, elibrary databases were used to identify studies that characterized the current view on the problem of choosing the optimal postoperative treatment for colon cancer.Results. the review showed the results of international studies of colon cancer subtypes based on complex multomics characteristics. Particular attention was paid to the description of modern studies on the search for prognostic markers for colon cancer. The relevance of the study of immunohistochemical markers was confirmed by the analysis of the world literature. the outcomes will make it possible to classify colon cancer into molecular subtypes in real clinical practice and, as a consequence, significantly improve the effectiveness of adjuvant therapy.

Publisher

Tomsk Cancer Research Institute

Subject

Cancer Research,Oncology

Reference68 articles.

1. Kaprin A.D., Starinsky V.V., Shakhzodova A.O. The state of cancer care to the population of Russia in 2019. Moscow, 2020. P. 72–75. (in Russian).

2. Kaprin A.D., Starinsky V.V., Petrova G.V. Malignant Neoplasms in Russia in 2018 (Incidence and Mortality). Moscow, 2019. P. 135–136. (in Russian).

3. American Cancer Society. Саncer Facts and Figures-2020. Atlanta, GA, 2020. P. 13–15.

4. SEER Cancer Statistics Review, 1975–2014 [Internet]. https://seer.cancer.gov/csr/1975_2014/ (cited 03.12.2020).

5. Gunawardene A., Desmond B., Shekouh A., Larsen P., Dennett E. Disease recurrence following surgery for colorectal cancer: five-year follow-up. N Z Med J. 2018 Feb 2; 131(1469): 51–58.

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Relationship of the epithelial-mesenchimal transition expression markers with clinical and morphological parameters of colon cancer;Siberian journal of oncology;2022-09-03

2. Overall survival in colon cancer patients with different levels of circulating tumor cells and feasibility of enhancing its prognostic value;Siberian journal of oncology;2022-09-02